The present invention provides a compound tablet capable of controlling release of effective component after oral administration, and makes it possible to control the release of water soluble medicineand water insoluble medicine. The compound orally administrated tablet contains both water soluble medicine and water insoluble medicine, the water soluble medicine is coated with polymer material toform delayed released granules the slow release n certain rule, and the water insoluble medicine is released fast. The preparation process of the present invention includes the first preparation of delayed released granules of water soluble medicine, the subsequent preparation of fast released water insoluble medicine, and final mixing and tabletting in a conventional rotary tabletting machine.