A control of a full-automatic plastic filling and blowing and hollow molding machine of a PLC-high speed singlechip-PIC singlechip includes a PLC- high speed singlechip system which consists of a PLC,a high speed singlechip, a level conversion circuit and a current direction control circuit, a temperature control module which consists of a signal magnifying circuit of a N-path temperature sensorand a driving circuit of a N-path heating device, a hydraulic pressure control system which consists of a PIC singlechip and a driving system of a hydraulic pressure control device, a pneumatic control module and a control panel. The method of using the device of the present invention to automatically control the filling and blowing process of the full-automatic plastic filling and blowing and hollow molding machine includes obtaining the system information, controlling the mechanical motion, controlling the temperature during the process of filling and blowing and controlling a hydraulic pressure flux and constant current of electric current of an electro-liquid proportional valve, and the obtaining of the system information has two routes of a PLC control procedure and a touch-screen interruption disposal. The control has high automatization degree and reliability, friendly human-machine interface, high cost performance of the system and the simple, convenient and practical method.