The invention discloses an intelligent safe management system, which integrates the personnel location, the attendance, the searching, the risk gas monitoring, the speech communication and the production process monitoring. A monitoring center server and an operating terminal are connected with a wireless communication device through a switch. A wireless intelligent sub-station is connected with the switch through an optical cable. A wireless ad hoc network is formed among the wireless intelligent sub-station, the wireless communication device and an intelligent location card. A production process monitoring unit is connected with the switch through the wireless intelligent sub-station or the wireless communication device. A software system is used for the collection, the recognition, thetransmission, the monitoring and the management of information. The software system can accurately monitor, locate and manage underground work personnel. A hand-held searching device can be used for finding the location card under emergency conditions. And the movement path of the location card is displayed in real time or reappears on the operation terminal. A risk gas sensor can transmit monitoring data in the region to the monitoring center server. Talking is possible among wireless talking devices and a control center above a well.