A method and apparatus for D-cache miss prediction and scheduling is provided. In one embodiment, execution of an instruction in a processor is scheduled. The processor may have at least one cascaded delayed execution pipeline unit having two or more execution pipelines that execute instructions in a common issue group in a delayed manner relative to each other. The method includes receiving an issue group of instructions, determining if a first instruction in the issue group resulted in a cache miss during a previous execution of the first instruction, and if so, scheduling the first instruction to be executed in a pipeline in which execution is delayed with respect to another pipeline in the cascaded delayed execution pipeline unit.