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发明授权
CN101032553B 一种治疗口腔溃疡的中药及生产方法 失效 - 权利终止

一种治疗口腔溃疡的中药及生产方法
摘要：
一种治疗口腔溃疡的中药，辅料为甘油、CMC-Na和PVA-1750，制成载药层、过渡层和隔离层；青黛和儿茶均匀分散在载药层中，载药层由甘油、1％CMC-Na溶液制备成，载药层中青黛与甘油之比为1∶2-4，儿茶与1％CMC-Na溶液之比为1∶4-8，晾干后载药层厚度为0.2-0.3mm；过渡层由PVA-1750和CMC-Na及15-25倍量蒸馏水制备成，PVA-1750与CMC-Na的配料比为8-10∶1，过渡层晾干后厚为0.2-0.3mm，铺于载药层上；隔离层由PVA-1750和甘油制备成，PVA-1750与甘油之比为8-10∶1，隔离层晾干后厚为0.2-0.3mm，辅于过渡层上。本发明能在水浸后成为溶胶，粘附在粘膜表面，膜内药物的释放持久，保持局部药物有效浓度，并使病损部位得到机械性的保护，故较其他给药方式如含片、散剂、含漱剂等更能减轻痛苦，提高疗效。
摘要（英）：

The Chinese medicine for treating stomatocace consists of one medicine carrying layer, one transition layer and one isolating layer. The medicine carrying layer prepared with glycerin and 1 % concentration CMC-Na solution carries homogeneously distributed natural indigo and catechu and has thickness of 0.2-0.3 mm; the transition layer on the medicine carrying layer is prepared with PVA-1750 and CMC-Na in the weight ratio of 8-10 to 1 and distilled water in 15-25 times and has thickness of 0.2-0.3 mm; and the isolating layer on the transition layer is prepared with PVA-1750 and glycerin in theweight ratio of 8-10 to 1 and has thickness of 0.2-0.3 mm. The Chinese medicine become sol after being soaked in water, and the sol is adhered to the surface of mucous membrane to maintain effective medicine concentration. It has high curative effect and less pain.

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