The invention belongs to the technical field of image process and the vision resume, specifically a Daltonism antidote based on the adaptive mapping. The method firstly builds a Daltonism simulation model, then makes the analysis process on the original image, to divide the project area according to the obtained number of color and the color distribution, finally builds the one-to-one mapping relation from the normal color space to the color blindness color surface according to the size of the color frequence and the projecting, and rectifies the original image according to mapping relation. The aim of the invention is to advance the ability of distinguishing the color for the Daltonism antidote, to make the information not displayed in the original image clearly display in the rectified image and the image process is carried through outside the eye, which does not damage the eyes, thereby having stronger feasibility about the cure and the rectification for the Daltonism.