The invention provides a method of interface topic replacement, which includes: accept the request of client side; analyze the interface topic resources of client side loading request, according to client side request; locate the requested interface topic resources and determine the class path of the requested load interface topic resources and load determined interface topic resources. The invention can realize the management of interface topic and web application system needs no code modification and no re-deployment to increase new interface topic resources. The invention can increase any interface topic resources, greatly improve the extensibility of the interface topic management and also discloses a system of interface topic replacement.