The invention relates to an electron beam irradiation sterilization equipment. The movable electron beam irradiation sterilization equipment of the invention consists of an electron beam irradiation accelerator and the control system, a vehicle chassis, a cabin installed on the chassis, an exhaust equipment and a power system installed in the cabin. The electron beam irradiation accelerator is installed in the cabin. The active effects of this invention are that: the electron beam irradiation accelerator and the control system, exhaust equipments and power system are all installed in the cabin of the vehicle chassis with small volume and mobility and flexibility, which can quickly shift in short time and has no special requirements on the applying environment and no extra construction. The invention can rapidly and thoroughly sterilize various kinds of documents and mails to keep them safe, without any damage on the radiated articles or any radiation remaining. Due to high automated integration, easy operation and safety, the invention is suitable to be applied in many domestic and international important organs.