The invention relates to calcium sulfonate complex grease and a manufacture method thereof, in particular to grease producing the thickening agent by synthetic reaction with super-high base value. At first, the lubricating base oil and the calcium sulfonate are added into an opening reaction kettle to be stirred, the phase inversion promoter, the glacial acetic acid and the water are added into the kettle to boost the temperature to make the insulating reaction until the materials are thickened, then the calcium hydroxide, the aliphatic acid and the boric acid are added into make an insulating reaction, a temperature rise, an insulating dehydration and a refining in turn, then the materials are moved into an intermediate kettle, the antioxidant is added to disperse and homogenize, and the finished product is produced after the filtering. The invention has excellent anti-spray performance, excellent high temperature performance, good extreme pressure anti-abrasion performance, prominent anti-shear performance, good pumping performance, anti-rust performance and water adding shear stability; has apparent phase inversion effect and good product performance, decreases the grease exchange times under the same working condition and increases the service life of the equipment, which is proved by the trial applications of a plurality of appliance manufacture enterprises, steel works, paper mills and so on.