The invention provides a sorbent used for removing iodide in organic medium, in particular to macroporous crosslinking ion exchange resin loaded with one or a plurality of metal ions. The metal ions loaded is one of silver, Hg and Pd, and mol loading of the metal ions is 1-90 percent of active sites of the ion exchange resin; the macroporous crosslinking ion exchange resin comprises two functional groups containing sulfonic group and carboxyl. A preparation method of the invention is that: through the initiation of azo-bis-iso-heptonitrile, acrylonitrile is suspension copolymerized with divinylbenzene monomer to obtain corsslinking polymer beads, pore-forming agent of which is extracted and washed out by solvent, thus obtaining the invention through sulfonation and ion exchange loading metal ions; the mol loading of the metal ions is 1-90 percent of the active sites of the ion exchange resin. Ceiling temperature used by the sorbent is 90 DEG C, liquid hourly space velocity is 1-15hr<-1> when ion-exchange column is used for removing iondine. The sorbent can remove the iondine ions in acetic acid below 5ppb.