The invention relates to a feedstuff used for culturing Penaeus vannamei. The composition of the feedstuff comprises one-level Peru fishmeal powder, one-level homemade fishmeal powder, soybean meal, peanut meal, beer yeast, cotton meal, shrimp shell powder, cuttle fish grease, refined fish oil, soybean phospholipids, flour, primary calcium phosphate as well as additive containing vitamin and microelement. The feedstuff also comprises medical herbs which comprise dyers woad leaves, dyers woad, common andrographis, radix bupleuri, fructus aurantii, herba houttuyniae, astragalus root, radix codonopsis pilosulae, red sage root, hemlock parsley, fresh angelica and fresh liquorice. The medical herbs formulation has positive effects of preventing diseases and the Penaeus vannamei that eat the feedstuff containing the medical herbs has relatively high survival ratio.