A bentonite sewage handling method is to grind the calcium base or the sodium base or the acid bentonite into 101 to 600 meshes and then pour the calcium base or the sodium base or the acid bentonite into the awaiting sewage to stir. Then, 24 percent of octadecyl trimethyl ammonium chloride is poured into the sewage and stirred; then a flocculent is poured into the sewage and stirred and settled,and the water-soil separation, microorganism treatment and standard discharge are carried out. The weight ratio of the sewage and any kind of bentonite is 1000:0.1 to 1000:1.0; the dosage ratio of the bentonite and the octadecyl trimethyl ammonium chloride is 1:1 to 1.5:1; the dosage ratio of the bentonite and the flocculent is 1:1.5 to 4:1. The method can be used for treating hotel sewage and oilfield sewage and has the advantages of low treatment cost, wide application range, and less sludge deposit. Furthermore, the method does not affect the successive microorganism treatment.