The invention provides a nonaqueous electrolyte secondary battery using the positive electrode active material having different physical properties, which is capable of being charged at a high charging voltage of more than 4.3 V and 4.6 V or less versus lithium without lowering the battery capacity, and has excellent charging/discharging cycle property and excellent charged storage properties. The positive electrode active material of the nonaqueous electrolyte secondary battery in the invention contains lithium and cobalt multiple oxid added with at least zirconium and magnesium, lithium nickel manganese multiple oxid with the layer structure, wherein the lithium and cobalt multiple oxid has different content of the zirconium and at least two zirconium, magnesium lithium and cobalt multiple oxid. The charging potential of the positive electrode active material is more than 4.3 V and 4.6 V or less versus lithium.