The invention relates to a device (1) for separating blood individually and/or in groups of components thereof, in the form of a sterisable system comprising a filter arrangement (2), which forms an inlet chamber (4) and an outlet chamber (5) by means of a filter element (3) which is arranged therein, a receptacle (6) for cellular blood components and a receptacle (7) for blood plasma.The inlet chamber (4) of the filter arrangement (2) can be connected to the blood source (10) via a line on the inlet side and is connected, on the outlet side, to the receptacle (6) for cellular components of the blood. The outlet chamber (5) is connected to the receptacle (7) for blood plasma via a line on the outlet side.; The aim of the invention is use thermal sterilisation, in particular vapour sterilisation, in order to sterilise said device.Said aim is achieved by virtue of the fact that a line (17, 20) is connected to the inlet-sided line (14) of the inlet chamber (4) or to the inlet chamber (4)and to the outlet-sided line (20) of the outlet chamber (5) or to the outlet chamber (5), in order to join towards the environment via a hydrophobic or hydrophilic filter, in particular hydrophobic or hydrophilic bacteria filter (18, 21).