The invention is a process for preparing a rare earth oxide macroporous material, which takes rare-earth salts or rare earth oxides as sources of metal ions and an L-asparagine as an organic ligand, and adopts the method of hydro-thermal synthesis to prepare a macropore rare earth coordination polymer precursor {Ln[(Asp)m(Asn)n]}p. Wherein, the Ln is La, Ce, Pr, Nd, Sm, Eu, Gd, Dy, Er and a plurality of mixtures thereof; and the Asp is an aspartic acid and the Asn is an asparagine. The obtained macropore rare earth coordination polymer is calcined in air, then the corresponding rare earth oxide macroporous material can be obtained. The rare earth oxide macroporous material prepared by the process of the invention has high yield and the macropore aperture is between 1 and 100 mu m. The process of preparation has advantages of environment protection, simplicity, low cost and easy mass production. The obtained material has good application prospect in fields such as catalysis, optics andchromatogram.