The invention relates to a high density biochip home position combiner, which belongs to the technical field of the biochip preparation. The high density biochip home position combiner is integrally composed of a biochip synthetic platform and a three-dimensional rectangular robot system, and the biochip synthetic platform is embedded and fixed at the bottom of the three-dimensional rectangular robot system. Wherein the three-dimensional rectangular robot system is composed of a linear motor servo system and a manipulator, and the linear motor servo system is composed of a linear motor X-Y platform, a servo driver, a PC computer and a servo motion control card. The manipulator is installed on the positioning head of the linear motor X-Y platform and is composed of a small-sized precision pneumatic sliding table and a vacuum chuck, to realize the functions of glass slide grabbing and impression. The biochip synthetic platform is composed of a base seat, four micro fluid self-driven devices of identical construction, a multifunctional spray pond and an automatic fluid filling device and the micro fluid self-driven devices is connected with the automatic fluid filling device through a fluid filling tube.