The invention relates to a medicine for treating kidney calculi, which takes herba lysimachiae, corn beard, lygodium japonicum, raw oysters, malva verticillata L, etc. as raw materials which are boiled out with water. And the decoction solution is concentrated and dried to be made into capsules. The medicine of the invention can eliminate and reinforce simultaneously and activate blood circulation to dissipate blood stasis and is applied to the treatment of kidney calculi and calculus in urinary system. The medicine can also prevent calculi infection, can relieve the pains of patients, protect renal function, try to remove calculi and prevent the recurrence. Clinical 586 cases of the patients with kidney calculi validates that the total effective rate of the medicine of the invention reaches to 95.9 percent and the drug of the invention has the advantages of good taste, fast efficacy and less side effects.