The invention belongs to craftware technical field, which provides a method for making a leather painting. The method for making a leather painting comprises the following steps: cutting a painting base plate from a plate according to the size of the painting; carving an original shape of the painting according to the painting pattern; making the carved pattern into a mold; forming a resin original shape from the mold with resin; sticking the resin original shape onto the base board; cutting a processed color leather according to the color of the pattern surface; sticking the cut leather ontothe fixed resin original shape; erasing the other colors of the discolored leather but remaining the ground color with dissolvent according to the pattern color, and then obtaining the required leather painting. According to the method of the invention, leather painting can be made in simple process, all the process can be carried out in large-scale industrially, and the produced leather paintinghas a strong three dimensional sense. The color leather is polished according to the convex and concave of the painting so as to give the leather painting a sharp distinct gradation, which along withthe inborn luster of the leather makes the whole painting a high quality.