The invention discloses a multi-configuration module device and an auto-configuration method. The multi-configuration module device comprises a processor, a configurable module and a configuration information storing device. After the device is electrified, the processor automatically reads configuration information stored in the configuration information storing device and the configuration information is used as the information of the configurable module for the initial configuration of the device. With the completion of the power-up initialization, the device enters into the mode of normaloperation in virtue of the configuration information. And then, an auto-configuration module carries out actual configuration detection to check the configuration information read from the configuration information storing device. When the information of the configurable module for the device is matched with the configuration information from the configuration information storing device, the correctness of the used configuration information is confirmed and the normal operation mode of the device is also confirmed, so the device can continue working normally. The configuration method adopted by the invention is that the configuration information is used firstly and confirmed thereafter, so the multi-configuration module device does need to spend additional time on checking the actual configuration of a hardware module, thus greatly shortening the time of the power-up initializing routine for software. So the multi-configuration module device is especially applicable for a plug-in module device that places strict restrictions on the power-up time.