The invention discloses a connection structure of lamp tube guide wires of an energy-saving lamp and a PCB board. The energy-saving lamp comprises an upper cover, the PCB board, a lower cover, four lamp tube guide wires and four small tinning springs; four spring sleeve columns are arranged on the lower cover; four mounting holes are arranged on the PCB board; each lamp tube guide wire runs through a corresponding small tinning spring which is sheathed on a corresponding spring sleeve columns; the four mounting holes of the PCB board are positioned on the lower cover after running through the four corresponding spring sleeve columns and cause the PCB board to contact with the small tinning springs. The connection structure of the invention realizes the electrical connection of the lamp tube guide wires and the PCB board by the small tinning springs, well solves the problem that the lamp tube guide wires touch welding points, improves the manufacturing efficiency of the traditional wire winding manner, is also beneficial to disassembling the PCB board so as to repair defective energy-saving lamps in the manufacture process, and has strong maneuverability and low cost when in production.