The invention discloses a high-speed peripheral interconnection interface of a compatible universal serial bus interface, which comprises a power terminal, a ground terminal, and four data terminals including two data sending terminals and two data receiving terminals; the power terminal and the ground terminal of the interface are in conformity with the corresponding terminals of the USB interface specification, thereby ensuring that the position and the width of two data terminals among four data terminals are overlapped with the D plus terminal position in the USB interface specification and not overlapped with the D minus terminal position in the USB interface specification, and guaranteeing that the position and the width of the other two terminals are overlapped with the D minus terminal position in the USB interface specification and not overlapped with the D plus terminal position in the USB interface specification. By adopting the PCI Express interface of the compatible universal serial bus interface, a data transfer rate up to 3Gb/S can be provided in accordance with the PCI Express interface specification; meanwhile, on the condition of not doing transformation to traditional USB peripheral equipments, a support to the peripheral equipments can be provided; in addition, the high-speed peripheral interconnection interface has the advantages of small outline dimensionand easy use.