The invention relates to a method for preparing ethyl-demethy laminothiazolyloximate, which comprises the following steps: oximate is performed on acetylacetic ether by using nitrous acid ester in alcohol solvent, and then cyclization is performed between the solution and thiourea through bromination to prepare ethyl-demethy laminothiazolyloximate. The method mainly has the beneficial effects that both oximate and bromination intermediates need no separation and purification, and are used in the next reaction directly, so the operating steps are simplified, the route is advanced, the reactioncondition is mild, the operating steps are simplified, the unit operation is avoided, the post-processing is simple, the manufacture cost is low, the yield is higher, the production of the three wastes is less, and more important implementary value and the social and economic benefits are realized.