A multi-degree-of-freedom artificial hand control device based on a multiple force sensing resistance sensor relates to a multi-degree-of-freedom artificial hand control device, which is provided for solving the shortcomings of the muscle surface electrical signal artificial hand control device of weak interference resistance, poor biomimetic performance and few control modes. The multi-degree-of-freedom artificial hand control device is composed of an information collection module, a signal analysis and processing module, a DSP-based artificial hand control module, etc; the information module is composed of a force sensing resistance sensor and a circuit switching processing module; the force sensing resistance sensor is installed at the inner side of an artificial limb tube, which coincides with the shape of the forearm, and fully contacts the forearm muscle; the signal output end of the force sensing resistance sensor is connected with the signal input end of the circuit switching processing module; the output end of the information collection module is connected with the signal input end of the signal analysis and processing module; the digital signal output end of the signal analysis and processing module is connected with the digital signal input end of the DSP-based artificial hand control module. The multi-degree-of-freedom artificial hand control device has the advantages of high interference resistance, good biomimetic performance, many control modes and high sensitivity.