The invention belongs to the medicine technology field, which more particularly relates to an ertapenem compound containing hydrosulphonyl pyrrolidine formamide triazine, the pharmaceutically acceptable salt thereof, the ester which is easy to be hydrolyzed, the isomer thereof, the hydrate thereof and the hydrate of ester or salt thereof shown in the formula (I) and a preparing method of the compound shown in the formula (I); wherein, the definitions of R<1>, R<2>, R<3>, R<4>, R<5> and R<6> are described in the specification. The invention also relates to preparing methods of compounds and the drug combination containing the compounds and the applications of the compounds in preparing the medicine for treating or preventing infectious diseases.