The invention relates to a method for configuring a concentrated transmission device of a large-scale multi-web roll straightener. Straightening rolls 2 are averagely divided into two sets; each of the two sets of the straightening rolls are connected through universal couplers 3 with the same number, unequal length and symmetrical distribution; the universal couplers in two sets are connected with a left main drive 1 and a right main drive 4 respectively which have the same structural form; the axial lines of the universal couplers which are connected up and down are intersected; and the axial lines of the output shaft of a speed reducer are intersected and an angle of the axial lines is more than 90 degrees. Both of the left main drive and the right main drive consist of a front distributor 5, a crowned gear type coupler 6, the speed reducer 7, a dowel pin coupler 8, a rear distributor 9 and a motor 10 respectively. The left main drive and the right main drive are symmetrically arranged; the output shaft of the front distributor is connected with three universal couplers; and the output shaft of the rear distributor is connected with two universal couplers. The configuration method is obviously the most scientific and reasonable, embodies reasonable length distribution and even stress of each universal coupler, does not add floating support and effectively reduces the unevenness of dynamic load.