An edge detection method using raising frequency sampling, a mobile detection thereof, a pixel interpolation thereof and the interrelated device thereof are disclosed. The pixel interpolation method is used for interpolating a pixel value generating an objective image in an objective picture. The pixel interpolation method comprises that the raising frequency sampling is carried out on the objective picture so as to generate a raising frequency picture corresponding to the objective picture; the interpolation is carried out on the objective pixel according to the raising frequency picture. According to the invention, the accuracy of the edge or mobile detection can be improved and the image quality of the interpolated image is improved.