The invention relates to an etherification reaction method for isomeric olefine. Alcohol and a raw material of the isomeric olefine are fed into a magnetic stabilized bed reactor and subjected to contact reaction with magnetic strong acid resin, the molar ratio of the alcohol to the isomeric olefine is between 0.2-4:1, the reaction temperature is between 35 and 95 DEG C, the reaction pressure is 0.1 to 4MPa, the liquid volume airspeed is 1 to 100 h<-1>, and the magnetic field intensity of the magnetic stabilized bed reactor is 10 to 1,500 oersteds. The method uses the magnetic strong acid resin to catalyze the isomeric olefine to carry out etherification reaction in the magnetic stabilized bed reactor, improves the effects of mass transfer and heat transfer of a reaction system greatly, and reduces energy consumption. In actual operation, the method can load and unload a catalyst at any time and carry out ex-situ regeneration without stopping running of the device.