The invention discloses a mobile intelligent safety guard monitoring system which consists of a central monitoring server, base station nodes, a plurality of route nodes, a target node and image acquiring nodes. The central monitoring server includes a public known computer, a digital monitoring map and a monitoring serving processing module; in which, the digital monitoring map and the monitoring serving processing module are stored in the memory of the public known computer; the digital monitoring map is constructed in network mode comprising route nodes, base station nodes and image acquiring nodes, for transforming the really arranged areas needing safety guard monitoring into digital plane map displayed on computer; the central monitoring server and the base station nodes are connected by cable, the image acquiring nodes and the base station nodes are connected in wireless mode, and the base station nodes and the route nodes are connected in wireless mode. When a monitored object moves, the monitoring system of the invention locates and tracks the object in real time according to its position after moved and the intensity of the signal sensed by the sensor in network.