The invention relates to a desinsection composite and application thereof. The effective components are Nitenpyram and crotonylfipronil; the weight portion ratio of the Nitenpyram to the crotonylfipronil is 20:1-1:20. The desinsection composite can be processed into any preparation formulation acceptable to pesticide application; the preferable preparation formulation is wettable powder, aqueous emulsion, missible oil, microemulsion, water dispersible granule or troche, and suspending agent. The disinsection composite is used for controlling pests on plants, especially for controlling the homoptera pests which generate resistance like plant hopper, leafhopper, white fly, and the like.