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发明公开
CN101453996A 药物递送组合物 失效 - 权利终止 转让 复审申请

药物递送组合物
摘要：
一种包含挤出球状体的药物递送组合物。所述球状体包含至少一种活性医药成分；至少一种挤出－滚圆助剂；至少一种超崩解剂；和至少一种助流剂、至少一种润滑剂、和/或至少一种油。所述球状体也可经涂覆。另一方面，药物递送组合物包含经涂覆球状体，所述经涂覆球状体具有惰性球状体和至少一个用于所述球状体的涂层。所述涂层包含至少一种活性医药成分和至少一种超崩解剂。
摘要（英）：

A drug delivery composition that comprises extruded spheroids. The spheroids comprise at least one active pharmaceutical ingredient; at least one extrusion-spheronization aid; at least one superdisintegrant; and at least one glidant, at least one lubricant, and/or at least one oil. The spheroids may also be coated. In a further aspect, a drug delivery composition that comprises coated spheroids that have inert spheroids and at least one coating for the spheroids. The coating comprises at least one active pharmaceutical ingredient and at least one superdisintegrant.

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