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发明公开
CN101468019A 头孢布烯缓释片 无效 - 撤回

头孢布烯缓释片
摘要：
本发明属于药物新技术领域，涉及头孢布烯的一种新剂型，用于治疗上呼吸道感染如咽炎、扁桃体炎、猩红热、副鼻窦炎、中耳炎；下呼吸道感染如急性支气管炎、慢性支气管炎急性发作、肺炎；泌尿道感染；肠炎及胃肠炎。该新剂型的特征在于本品为缓释片，在水或规定的释放介质中缓慢的非恒速的释放药物。本发明的缓释片通过缓慢释放，使药物在体内达到一个稳态的血药浓度水平，减少药物不良反应的发生和减少耐药菌株的产生。
摘要（英）：

The invention belongs to the novel technology field of the medicines and relates to a novel dosage form of ceftibuten for treating: upper respiratory tract infection such as pharyngitis, antiaditis, scarlet fever, paranasal sinusitis, and otitis medium; lower respiratory tract infection such as acute bronchitis, acute attack of chronic bronchitis and pneumonia; urinary tract infection; enteritis and gastroenteritis. The novel dosage form is characterized in that the dosage form is sustained-release tablets and can release medicines in a low and unsteady speed in water or specified release medium. The sustained-release tablets of the invention can make the medicines reach a steady blood-drug concentration level in vivo through releasing slowly, decrease adverse drug reaction and reduce the generation of drug-resistant strain.

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