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发明授权
CN101502523B 苯甲酰氟苯水杨酰胺类化合物在制备抗肿瘤药物中的应用 失效 - 权利终止 许可

苯甲酰氟苯水杨酰胺类化合物在制备抗肿瘤药物中的应用
摘要：
本发明公开了如式(I-1)～式(I-12)所示之一的苯甲酰氟苯水杨酰胺类化合物在制备抗肿瘤药物中的应用。本发明提供了一种新的有显著抗肿瘤活性的抗肿瘤药物，为新药筛选提供了研究基础；其中，式(I-10)或式(I-11)所示的化合物具有非常显著的抗肿瘤作用，式(I-2)、式(I-3)、式(I-4)、式(I-5)或式(I-9)所示的化合物具有显著的抗肿瘤作用，式(I-1)、(I-6)、(I-7)或(I-8)具有较好的抗肿瘤作用，式(I-12)所示的化合物具有一定的抗肿瘤作用。
摘要（英）：

The invention discloses the application of benzoyl fluorobenzene salicylamide type compounds as shown in formula (I-1) to formula (I-12) in the preparation of anti-tumor drugs. The invention provides a novel anti-tumor drug having significant anti-tumor activity and provides the foundation for the research of drug-screening, wherein, the compound as shown in formula (I-10) or formula (I-11) has very significant anti-tumor effect; the compound as shown in formula (I-2), formula (I-3), formula (I-4), formula (I-5) or formula (I-9) has significant anti-tumor effect; the compound as shown in formula (I-1), formula (I-6), formula (I-7) or formula (I-8) has better anti-tumor effect; and the compound in formula (I-12) has certain anti-tumor effect.

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