The invention provides a breeding method for high-oleic acid high-yield peanut, which includes steps: (1) coordinate parent combination: selecting high-yield germplasm with good integrated character and germplasm with high oleic acid content SPI098 to combine patent; (2) high oleic acid pressure screening: determining oleic acid of each seed in excellent single plant in early separation generation, and selecting excellent peanut seed with high oleic acid content; (3) high-yield pressure screening: planting the screened peanut seed with high oleic acid content in next generation, separating generation in anaphase, and selecting excellent high-yield single plant; and (4) high-oleic acid high-yield peanut variety or strain obtaining: obtaining novel high-oleic acid high-yield peanut variety or strain through multi-generation high-oleic acid high-yield pressure screening. The breeding method provided by the present invention directly screens according to character of oleic acid content inpeanut seed, and has advantages of short breeding period, small blindness, high efficiency, and good economic benefit and social benefit.