The present invention discloses a one-class polarity fluobenzene based high-efficiency liquid phase chromatogram filler and a method for synthesizing the same. The silica gel surface of the chromatogram filler is bonded with polarity fluobenzene based functional groups, and the chemical structure of the filler is shown as the general formula(I):R<1>=C6F5-, C6F5CONH-, C6F5CONHC6H4-, or C6F5CONHC6H4O-; alpha is between 0 to 30, and beta is 0, 1 or 2; R<2> is a C1 to C20 alkyl group, cycloalkyl group, heterocyclic ring alkyl group or phenol group; and X is a halogen, alkoxy group, acyloxy group or amino group. The chromatogram filler has two liquid phase separation modes-positive phase and negative phase, and can be used in 0 to 100 percent of water or 0 to 100 percent of organic mobile phase and also be effectively used for separation analysis of acid, neutral and alkali compounds.