Compositions, such as lens precursor compositions, and methods for producing lens precursor compositions have been invented. The present methods include forming a premix composition, which can include one or more monomeric components, forming a macromer composition, which includes one or more silicon containing macromers, forming a premix/initiator composition, which can include a photoinitiator,and contacting the premix/initiator composition with the macromer composition to form a polymerizable monomer-containing composition useful in the production of producing silicone hydrogel contact lenses.