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发明授权
CN101536999B 3,5-二甲氧基-4-羟基苯甲醛在射线防护中的应用 有权

3,5-二甲氧基-4-羟基苯甲醛在射线防护中的应用
摘要：
本发明公开了3，5-二甲氧基-4-羟基苯甲醛的新用途。该新用途是3，5-二甲氧基-4-羟基苯甲醛在防护α粒子射线损伤中的应用。实验表明，在细胞体外培养并用α粒子射线辐照细胞的实验中，培养体系中添加了3，5-二甲氧基-4-羟基苯甲醛的细胞，辐照后其克隆形成率要明显高于未添加药物的细胞，由辐照引起的基因突变率也明显低于未添加的细胞。因此，3，5-二甲氧基-4-羟基苯甲醛可减轻射线辐照引起的基因组DNA损伤和基因突变，具有辐射防护作用。
摘要（英）：

The invention discloses a new use of 3,5-dimethoxy-4-hydroxy benzaldehyde which is an application of 3,5-dimethoxy-4-hydroxy benzaldehyde in alpha-particle ray damage protection. Test proves that, in the test of cell culture in vitro and ray irradiation with alpha-particle ray, the cell of 3,5-dimethoxy-4-hydroxy benzaldehyde is added in the culture system; the clone forming rate after irradiation is obviously higher than that of the cell without adding medicants, and the gene mutation rate caused by irradiation is obviously lower than that of the cell without adding medicants. Therefore, 3,5-dimethoxy-4-hydroxy benzaldehyde can reduce gene group DNA damage and gene mutation caused by ray irradiation and has the effect of irradiation protection.

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