The invention provides a human-machine interface (HMI) interactive system which comprises an input device, a storage bank, a search module, a display device, a call module, wherein, the input device is used for inputting keyword strings and transmitting the keyword strings to the display device, and the input device is further used for inputting select instructions and transmitting the select instructions to the call module after the target information object is searched by the search module; the storage bank is used for storing information objects; the search module is used for searching the information objects stored by the storage bank for the matching information object output module according to the inputted keyword strings, and the obtained information objects after search are transmitted to the display device; the display device is used for forming an input region on the displayed movable terminal desktop to display the keyword strings inputted by the input device and information object list outputted by the output device; the call module is used for selecting the target information object from the displayed information object list according to the select instructions inputted by the input device and calling the target information object; The invention further provides an HMI interactive method. The invention can search for the matching information object and directly call the properties of the information object by directly inputting keywords on the desktop of the mobile terminal, so that the information object can be searched and called more rapidly and conveniently.