The invention relates to a method and equipment for the pre-treatment of reaction produced gas in olefin preparation technology by oxygen-containing compounds, which aim to overcome the disadvantages that the reaction product gas in olefin preparation by the oxygen-containing compounds in the prior art has higher temperature and contains a small amount of catalyst. The method comprises the following steps that: the reaction produced gas in olefin preparation technology by the oxygen-containing compounds performs heat exchange and then enters a quench tower, the catalyst carried in the reaction product gas is scrubbed, the temperature of the reaction product gas is reduced at the same time, and then the reaction product gas enters a water scrubbing tower to further scrub the catalyst carried in the reaction product gas and then is sent to an olefin separation unit. The invention also discloses the equipment which is used for the method and consists of the quench tower and the water scrubbing tower, the inside of the quench tower is empty or is provided with a baffle or a tray, the inside of the water scrubbing tower is provided with a baffle, stuffing or a tray, and the bottom of the water scrubbing tower is provided with oil insulation facilities.