The invention provides a compound liniment for treating acne rosacea, which consists of the following raw materials by weight percentage: cyproheptadine, vitamin B6, sulfur, mercurous chloride, radix sileris, clove oil, borneol and the like. The compound liniment accords with the chemical characteristics of skin, is advantageous for giving play to physiological functions of the skin, is safe and reliable for treating the acne rosacea, can quickly deliver drugs to a pathologic change part to diminish inflammation, kill mites and sterilize powerfully, and play a direct action on the root of niduses to thoroughly dispel symptoms of itching, red, blains and the like of the acne rosacea. By combining with DS reparative factors, the compound liniment can repair the microcirculation of the skin in a short time, regulate sebum secretion metabolism, and reconstruct the immunologic function of normal skin to thoroughly cure the acne rosacea and prevent recurrent attacks; and in the using process, the compound liniment reduces the dryness and tension of nose skin, has small acrimony, can be accepted by patients easily, and has broad application prospect.