The invention discloses a Chinese traditional medicine combination for treating mastosis and a preparing method. The Chinese traditional medicine combination is prepared by dandelion, bupleurum root, angelica, nutagrass flatsedge rhizome (vinegar bake), radix salviae miltiorrhizae, root of herbaceous peony (fried), seed of cowherb, red peony root, bighead atractylodes rhizome (fried). The Chinesetraditional medicine combination has excellent function of clearing the liver and enrichingthe blood, regulating vital energy and dispelling melancholy without toxicity and side-effect and is adaptable to hypochondriac distress and pain, breast nodule and tenderness, breast pain before menstruation, abnormal menstruation and hyperplasia of mammary glands. Compared with the prior art, the invention has good prescription, high bioavailability and remarkable therapeutic effects.