The invention discloses a swirling flow reaction inclined tube sedimentation tank and belongs to the technical field of clean production and circular economy. The invention comprises a pool body and an inner tank; the inner tank is arranged in the centre of the circular pool body; the lower part of the inner tank is swirling mixing zone; the upper part thereof is vortex reaction zone; the space of the pool body outside the inner tank is contact filtration and gravity settling zone; a guide ring is arranged around the inner tank; a constant-current water distribution zone is arranged between the guide ring and the inner tank; a sump tank is arranged around the guide ring; a sedimentation inclined tube which is filled with stuffing is arranged below the bottom of the sump tank; one side of the sump tank is communicated with an effluent tank by a connecting tank; an effluent pipe is arranged on the bottom of the effluent tank; an inlet pipe is arranged on the lower part of the pool body and the end of the inlet pipe passes through the inner tank and enters the swirling mixing zone and is arranged together with a swirling water distributor. By using the swirling flow reaction inclined tube sedimentation tank of the invention, the precipitation efficiency is maximized; the energy consumption is reduced; the impact resistance capability is strong; the operating flexibility is high and the tank is easy to maintain.