The invention discloses an ultrasonic washing machine, comprising a bottle-in mechanism, a spraying mechanism, a washing mechanism, a bottle-out mechanism, a draining mechanism and a water tank; wherein, an bottle-out end of the bottle-in mechanism is inclined downward and is connected with an bottle-in end of the washing mechanism, the bottle-out end of the washing mechanism is inclined upward and is connected the bottle-out mechanism, the washing mechanism is arranged in the water tank, the spraying mechanism is arranged above the bottle-in mechanism, and the draining mechanism is arranged above the bottle-out mechanism. The ultrasonic washing machine of the invention has simple structure, low cost, and convenient operation, and the transmission components in contact with the bottle andthe cleaning medium do not enter into the next fine washing process.