The invention provides a system and a method for reducing the video region blocking effect. The system comprises a smooth filter, one or a plurality of variance value generators and a self-adaptive mixing unit. The method comprises the following steps: confirming a smooth handling coefficient value of an object pixel according to the object pixel and the characteristic function of the peripheral pixel of the object pixel; confirming one or a plurality of variance values according to the image detail degree around the object pixel; confirming the smooth handling capacity of the object pixel according to the smooth handling coefficient value and one or a plurality of variance values; and providing an output pixel according to the smooth handling capacity. The system and the method for reducing the video region blocking effect filter and perform smooth handling to the pixel based on other image details around each pixel, thereby reducing the blocking effect in a video image and improvingthe quality of the video image.