The invention discloses a frame frequency lifting method for combining target partition and irregular block compensation, which is characterized by comprising the following steps that: firstly, establishing a blank frame to be inserted; secondly, sampling a reference frame and the blank frame to be inserted; thirdly, calculating the frame difference between the reference frame and the blank frame to obtain a moving target outline and a moving target area mask by applying the morphological method; fourthly, partitioning the two reference frames into a target area and a background area; fifthly, moving and estimating subarea processing to obtain an initial motion vector; sixthly, smoothening the obtained initial motion vector; seventhly, trimming the initial motion vector after being smoothened to obtain a more accurate motion vector; eighthly, calculating the compensation weight coefficient Mu; ninthly, partitioning the block into a high relevant area and a low relevant area; tenthly, compensating subarea processing; and eleventhly, generating an interpolated frame. The method can be widely applied to the technical fields of video coding and encoding and video processing.