The telemetering data cleaning method for a data acquisition and monitoring control system relates to the technical field of data processing, and solves the technical problem of data quality improvement. The method is characterized in that a pattern list is set up at first, then real-time data is cleaned according to the pattern list, wherein the establishment of the pattern list comprises the following steps: the historical data over one month is grouped according to acquisition time, the arithmetic mean value of each group is calculated, then the historical data is revised according to an admission relation, the arithmetic mean value of each group is calculated again, and finally, a pattern list is set up according to the evaluated arithmetic mean value of each group; the cleaning of real time data comprises the following steps: finding a pattern value matched with the real-time data in the pattern list according to acquisition time, and then carrying out error judgment on the real-time data through the pattern value and maximal permissible error value so as to directly remove polluted data and provide reference data. By using the telemetering data cleaning method of the invention, higher data quality can be guaranteed.