The invention discloses a final-assembly die with a truss type spatial structure, which is structurally characterized in that a base is provided with a plurality of brackets, and the top ends of the brackets are provided with a micro-adjustment mechanism respectively. The micro-adjustment mechanism consists of a fixed disk, an adjusting disk, a lifting rod and a ball head support, wherein the fixed disk is fixed at the top end of the bracket; the adjusting disk is placed above the fixed disk and off-axially fixed with the fixed disk as a whole, and the adjusting disk is off-axially fixed witha disk seat placed above the adjusting disk as a whole so as to carry out adjustment in the horizontal direction; the lower end of the lifting rod is fixed at the central position of the disk seat tocarry out adjustment in the vertical direction; and the bottom of the ball head support is provided with a ball, the top of the ball head support is provided with a columnar strut, and the ball at the bottom is connected to a ball socket at the upper end of the lifting rod through a clamping cap so that the ball head support swings with the ball socket as center. The spatial position and normal direction vector of corresponding nodes of a curved surface can be designed according to the truss type spatial structure to carry out the adjustment of six freedom degrees, so the integral construction of the final-assembly die meets the requirement of designing the curved surface.