The invention provides five flavored health wine and a manufacturing method thereof. The five flavored health wine is manufactured by mixing traditional Chinese medicines, rice wine and sugar water; the health wine of invention is characterized by comprising the following traditional Chinese medicines according to parts by weight: 100 parts of schizandra, 90 parts of red ginseng, 80 parts of dwarf lilyturf root, 70 parts of pseudo-ginseng and 60 parts of prepared polygonum multiflorum; the blended weight ratio of the rice wine, five traditional Chinese medicines and sugar water is 69.2:0.8:30. The manufacturing method of the five flavored health wine is as follows: soaking the well-matched traditional Chinese medicines with the rice wine in a porcelain urn for 24 hours; then pouring the boiled sugar water into the urn and sealing for 60 days; waving and oscillating once every day for the first 30 days and placing the porcelain urn in a shade place for the later 30 days; filtering out the medicine residues with three-layer gauze after unsealing and standing for 6 days. The five flavored health wine has efficacies of alleviating or eliminating insomnia and headache, dizziness, heartbeat and spermatorrhea which are caused by neurasthenia, hypertension, coronary sclerosis, angina, impotence, early white hair and whiskers and the like, thus being an ideal health-care product.