The invention discloses an insect-killing composition containing etofenprox and buprofezin, comprising the effective active components of the etofenprox and the buprofezin, wherein the weight ratio of the etofenprox to the buprofezin is 2.5:1-1:4. The invention has reasonable components, good insect-destroying effect, low application cost, high quick-acting property, long lasting period and good safety without pollution on crops, little residual quantity of a preparation and obvious synergistic action, delays the generation of resistibility, and conforms to the safety requirement of a pesticide preparation; and the activity and the insect-killing effect of the invention are not the simple superposition of the activity of the components. The invention has the preventing effect of 87.46-96.93% to paddy rice planthopper after being applied 14 days.