The invention relates to a plaster for treating chronic gastroenteritis, which is prepared from the following raw materials: sesame oil, yellow lead, costus root, cinnamon, fructus evodiae, coptis root, white atractylodes rhizome, cumin, tuckahoe, villous anomum, hawthorn, zanthoxylum, dried ginger, borneol, azone and nano ceramic powder. The preparation method comprises the following contents: preparing an ointment substrate by the sesame oil and the yellow lead; grinding the borneol into powder which is sieved by a sieve of 110 meshes; after decocting other medicine materials with water, taking decoction, removing residues, concentrating the obtained medicine decoction and obtaining a medicine material extract; after dissolving the ointment substrate, adding the medicine material extract, the borneol powder, the nano ceramic powder and the azone to obtain the ointment; and spreading the ointment on a backing material so as to obtain the plaster. The plaster for treating the chronic gastroenteritis, which is provided by the invention, has the characteristics of accurate application, strong permeability and high content of effective components and has better curative effect for treating the chronic gastroenteritis.