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CN101643398A 一种2,3,4,4′-四羟基二苯甲酮的制备方法 无效 - 撤回

一种2,3,4,4′-四羟基二苯甲酮的制备方法
摘要：
本发明提供了一种2，3，4，4′-四羟基二苯甲酮的制备方法，所述方法包括：以环丁砜为溶剂，以焦性没食子酸和对羟基苯甲酸为原料，在负载型Lewis酸和三氯氧磷催化体系下，于120-160℃下保温反应6-10小时，过滤回收负载型Lewis酸催化剂，减压回收部分溶剂环丁砜后，中和，加适量蒸馏水，冷却析晶，抽滤，水洗干燥后得黄色目标化合物，收率可达80％以上；所述负载/蒙脱/蒙AlCl 3 式为下列之一：ZnCl 2 脱土。本发明与现有技术比较具有的优点为：(1)负载催化剂催化效率高，反应后易于分离，可回收利用，降低生产成本；(2)产品收率高，对环境友好，适于工业化大生产。
摘要（英）：

The invention provides a preparation method of 2,3,4,4'-tetrahydroxyldiphenylketone, comprising the following steps: adopting sulfolane as solvent and pyrogallol as raw materials to perform a reactionat 120-160 DEG C for 6-10h in the presence of a catalyst system containing supported Lewis acid and phosphorus oxychloride, recycling supported Lewis acid catalyst through filtration, reducing pressure to recycle partial solvent sulfolane, neutralizing, adding a defined amount of distilled water, cooling to precipitate crystal, washing with water and finally drying to obtain the yellow target compound, wherein the yield can reach above 80% and the supported Lewis acid is 4-6mmol/g of ZnCl2/montmorillonite, ZnBr2/montmorillonite or AlCl3/montmorillonite. Compared with the prior art, the invention has the advantage that (1) the catalysis efficiency of the supported catalyst is high and can be separated and recycled after the reaction, thus reducing the production cost; (2) the product yieldis high, the product is environmentally friendly and is applicable to mass industrialized production.

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